Amazon founder Jeff Bezos on his decision to start an online bookstore in the 1990s:

The framework I found which made the decision incredibly easy was what I called the regret minimization framework. I wanted to project myself forward to age 80 and look back on my life and I want to have minimized the number of regrets I have. And I knew that when I was 80 I was not going to regret having tried this. I was not going to regret trying to participate in this thing called the internet that I thought was going to be a really big deal. But I knew the one thing I might regret is not ever having tried. And I knew that that would haunt me every day. So when I thought about it that way it was an incredibly easy decision.

With unavoidable uncertainty and wild problems, sometimes regret minimization is the best paradigm we have.

// 01.28.26

Basecamp’s Jason Fried’s brief discussion of product development should be required reading for anyone who designs software, including EHRs, PACS, dictation, or whatever new dumb AI implementation someone is pitching to revolutionize healthcare (but that no one talked to an actual doctor about).

The critical tension is the balance between making features obvious, easy, and possible. You have to have opinions, and you have to choose, because being everything to everyone isn’t an option.

// 01.27.26

Our family had some nice, quiet snow days over the weekend here in Dallas, so I finally finished this historically interesting if morbid Lego mosaic of the first CT scan from 1971 (right frontal GBM):

The Stoics thought everyone should have a memento mori, but the typical skull is so staid.

// 01.26.26

I’m in the new episode 7 of AJR’s Radiology Trailblazers podcast with Dr. Lindsey Negrete and Dr. Amy Maduram. Please do not think for a second that I accept my inclusion in any “trailblazing” premise(!), but we had a nice discussion about the writing process in and out of radiology. Whenever I do a podcast, I am always able to create at least one new verbal tic. This time it was “in reality”—please forgive me.

// 01.21.26

Author Tim O’Reilly, in his 2006 commencement speech at UC Berkeley:

Money is like gasoline during a road trip. You don’t want to run out of gas on your trip, but you’re not doing a tour of gas stations.

// 01.21.26